期刊
JOURNAL OF NEUROIMMUNOLOGY
卷 187, 期 1-2, 页码 94-101出版社
ELSEVIER
DOI: 10.1016/j.jneuroim.2007.04.012
关键词
intestinal lymphocytes; apoptosis; exercise; corticosterone; caspase 3; HSP 70; antioxidant
The purpose of this study was to characterize the expression of apoptosis (caspase 3, Bcl-2) and survival (HSP 70, antioxidant CuZn-SOD) proteins in intestinal lymphocytes (IL) of mice after repeated exercise stress. Plasma corticosterone concentration was greater than twofold higher immediately after exercise compared with the non-exercised condition. IL numbers decreased 24 h after cessation of exercise (p < 0.05); this was associated with increased caspase 3 (p < 0.05), HSP 70 (p < 0.001) and CuZn-SOD (p < 0.05) expression in IL immediately after exercise relative to IL from non-exercised mice. Expression of these proteins returned to control levels 24 It after the cessation of exercise stress. (c) 2007 Elsevier B.V. All rights reserved.
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