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The Wnt signaling pathway and bone metabolism

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CURRENT OPINION IN RHEUMATOLOGY
卷 19, 期 4, 页码 376-382

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/BOR.0b013e32816e06f9

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beta-catenin; arthritis; low-density lipoprotein receptor related protein 5; sclerostin; Wnt

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Understanding the role that the Writ signaling pathways play in the regulation of bone metabolism offers great promise for the developmental of new paradigms and pharmaceutical strategies for the treatment of various 1 diseases such as osteoporosis, rheumatoid arthritis and osteoarthritis. Progress in this regard has already been made.

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