期刊
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
卷 334, 期 1, 页码 47-52出版社
ELSEVIER SCIENCE INC
DOI: 10.1097/MAJ.0b013e3180ca8c41
关键词
blood volume; heart failure; diagnostic testing; radioisotope
Symptoms of intravascular volume overload and increased cardiac filling pressures in the systemic and pulmonary venous circulations are among the most common complaints in patients with chronic heart failure (CHF). The clinical utility of physical examination for estimation of intravascular volume status in patients with CHF is limited due to poor specificity and sensitivity of most signs of congestion. Direct measurement of blood volume with radioisotope techniques is FDA-approved and has been shown to be closely associated with invasive measurements of cardiac filling pressures in patients with CHF. Unrecognized volume overload is common in CHF patients and is associated with adverse clinical outcomes. Additional work is needed to determine the clinical utility of serial blood volume measurements in the management of patients with CHF.
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