期刊
EUROPEAN JOURNAL OF CANCER
卷 43, 期 11, 页码 1694-1700出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ejca.2007.04.011
关键词
bladder cancer; prostate cancer; multiple primary neoplasms
类别
Objective: To assess the occurrence of both bladder and prostate tumours in five well defined cancer registries. Methods: Anonymous data were provided from each cancer registry on all male bladder and prostate cancers (invasive and non-invasive). Poisson regression was used to model the rate of developing the second primary tumour and generated incidence rate ratios (RRs) with 95% confidence intervals. Results: For bladder cancer and prostate cancer as first diagnosis, there was an excess risk to develop the second neoplasm. The RR decreased with increasing age of the patients. No effect of the initial treatment of the first neoplasm was found. Conclusion: This analysis found an excess risk to develop prostate cancer in bladder cancer patients younger than 70 years and the first year of follow-up after the diagnosis of bladder cancer. This may be due to detection bias, although a common aetiology may also be present. (c) 2007 Elsevier Ltd. All rights reserved.
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