Online-Calibration for Reliable and Robust Lab-on-a-Chip Surface Enhanced Raman Spectroscopy Measurement in a Liquid/Liquid Segmented Flow

Concerning the usability of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS) for analytical tasks applying chemometric data evalutation, a secure, reproducible, and stable data output independent of inconsistent ambient conditions has to be accomplished. In this contribution, we present a new approach to achieve reliable and robust measurements based on segmented flow LOC-SERS via online-wavenumber calibration.