期刊
ANALYTICAL CHEMISTRY
卷 81, 期 17, 页码 7281-7287出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac901026t
关键词
-
资金
- Queen's University
- Ontario Innovation Trust
- Canadian Foundation
- Natural Sciences and Engineering Research Council of Canada
Novel multichannel electrospray emitters are presented that use silica-based microstructured fibers (MSFs) to split the flow allowing efficient desolvation during electrospray. The MSFs investigated in this study possess 30-168 individual fluidic channels (each channel being 5 mu m in diameter) that form a 2D emitting array. Multiple flow paths afford stable electrospray at flow rates ranging from the microspray (e.g., 1000 nL/min) to the nanoelectrospray (e.g., 10 nL/min) regime with moderate to negligible flow-induced backpressures. The electrospray stability of highly aqueous solutions (up to 99.9% water with 0.1% acetic acid) is enhanced through modification of the emitting surface with a hydrophobic silylation reagent (chlorotrimethylsilane). Furthermore, by successfully spraying highly concentrated salt solutions, this study demonstrates that multichannel MSF emitters provide enhanced robustness to clogging, leading to increased operational throughput.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据