An optical sensing approach for the detection of saccharides based on reversible boronic acid-diol complexation in a lipophilic polymer membrane is presented. The complexation of saccharides with phenyl boronic acids that are immobilized in a hydrophobic polymer matrix produces a stable boronate anion and liberates a mobile hydrogen ion. The change in fluorescence intensity of the sensing films resulting from the increase in hydrogen ion concentration is thus directly related to the ambient saccharide concentration. By monitoring the pH change in a bulk optical film, we were able to detect D-glucose, D-fructose, D-galactose, and D-sorbitol with a concentration range from 0.1 to 100 mM at physiological pH 7.4.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据