Enantioselective synthesis of (R)-deoxydysibetaine and (-)-4-epi-dysibetaine

Enantioselective synthesis of (R)-deoxydysibetaine and (-)-4-epi-dysibetaine was achieved by employing a samarium iodide-promoted reductive carbon-nitrogen bond cleavage of a proline derivative, as a key reaction. (c) 2007 Elsevier Ltd. All rights reserved.