期刊
SYNLETT
卷 -, 期 11, 页码 1667-1670出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-984517
关键词
Michael additions; aldol reactions; asymmetric synthesis; domino reactions; organocatalysis
Chiral Substituted cyclohexene carbaldehydes are readily synthesized in excellent enantiomeric excesses from simple nitroketone and enal precursors. The domino Michael addition-aldol condensation reaction catalyzed by a chiral secondary amine involves tandem iminium-enamine activation.
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