ERβ ligands.: Part 6:: 6H-chromeno[4,3-b]quinolines as a new series of estrogen receptor β-selective ligands

A new class of estrogen receptor beta (ERP) ligands based on the 6H-chromeno[4,3-b]quinoline scaffold has been prepared. Several C7-substituted analogues displayed high affinity and modest selectivity for ERP. (C) 2007 Elsevier Ltd. All rights reserved.