Acridone-based inhibitors of inosine 5′-monophosphate dehydrogenase:: Discovery and SAR leading to the identification of N-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2-fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)