期刊
TETRAHEDRON LETTERS
卷 48, 期 31, 页码 5407-5409出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.06.005
关键词
TaBr5-catalyzed Biginelli reaction; solvent-free conditions; 3,4-dihydropyrirnidin-2-(1H)-ones/thiones
An efficient TaBr5 (5-10 mol %)-catalyzed Biginelli reaction under solvent-free conditions for one-pot syntheses of 3,4-dilhydropyrimidin-2-(] H)-ones (DHPMs) and their thione analogs is reported. The catalyst is stable at room temperature and employed under mild and environmentally friendly conditions. (c) 2007 Elsevier Ltd. All rights reserved.
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