Application of retrovirus-mediated expression cloning for receptor screening of a parasite

Retrovirus-mediated expression cloning has been applied in both virology and cell biology. Although there is some difficulty in applying this technique to screening for a receptor recognized by an intracellular parasite, we modified the conventional method to identify a putative receptor for the Plasmodium falciparum BAEBL protein. We show that this method is effective in screening for a parasite receptor. (C) 2009 Elsevier Inc. All rights reserved.