期刊
AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 166, 期 3, 页码 289-295出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/aje/kwm073
关键词
abruptio placentae; pregnancy; recurrence; risk; smoking
资金
- NICHD NIH HHS [HD038902] Funding Source: Medline
The authors examined associations between cumulative smoking during a woman's first and second pregnancies and risk of placental abruption in the second pregnancy. They performed a population-based prospective cohort study of 526,690 women who delivered their first two consecutive singletons in Sweden in 1983-2001. Using logistic regression models, the authors found that, among women without placental abruption in the first pregnancy, smoking was associated with increased risk of abruption in the second pregnancy; however, this effect was confined to exposure occurring during the second pregnancy (adjusted odds ratio (OR) = 1.8, 95% confidence interval (CI): 1.4, 2.3) but not the first (adjusted OR = 1.1, 95% CI: 0.9, 1.3). Among women with a prior abruption, the risk of repeating abruption was increased irrespective of smoking habits. When women smoked during both pregnancies, there was an almost 11-fold increase in risk (adjusted OR = 10.9, 95% CI: 7.3, 16.3). These findings suggest that women who quit smoking before pregnancy may benefit from reduced risk of abruption. The observation that the recurrence of abruption is substantially increased regardless of changes in smoking habits suggests that factors other than smoking may influence the recurrence of placental abruption.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据