期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 405, 期 10, 页码 3205-3214出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-013-6722-7
关键词
Frontal polymerization; Molecularly imprinted polymer; Molecular recognition; Affinity; Levofloxacin
资金
- National Natural Science Foundation of China [21075090]
- Hundred Talents Program of the Chinese Academy of Sciences
Frontal polymerization was successfully applied, for the first time, to obtain molecularly imprinted polymers (MIPs). The method provides a solvent-free polymerization mode, and the reaction can be completed in 30 min. By this approach, MIPs were synthesized using a mixture of levofloxacin (template), methacrylic acid, and divinylbenzene. The effect of template concentration and the amount of comonomer on the imprinting effect of the resulting MIPs was investigated. The textural and morphological parameters of the MIP particles were also characterized by mercury intrusion porosimetry, nitrogen adsorption isotherms, and scanning electron microscopy, providing evidence concerning median pore diameter, pore volumes, and pore size distributions. The levofloxacin-imprinted polymer formed in frontal polymerization mode showed high selectivity, with an imprinting factor of 5.78. The results suggest that frontal polymerization provides an alternative means to prepare MIPs that are difficult to synthesize and may open up new perspectives in the field of MIPs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据