期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 397, 期 3, 页码 967-972出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-010-3556-4
关键词
Deuterium; Protein mass spectrometry; Protein dynamics; Protein conformation
资金
- National Institutes of Health [R01-GM070590, R01-GM086507]
Proteins are undoubtedly some of the most essential molecules of life. While much is known about many proteins, some aspects still remain mysterious. One particularly important aspect of understanding proteins is determining how structure helps dictate function. Continued development and implementation of biophysical techniques that provide information about protein conformation and dynamics is essential. In this review, we discuss hydrogen exchange mass spectrometry and how this method can be used to learn about protein conformation and dynamics. The basic concepts of the method are described, the workflow illustrated, and a few examples of its application are provided.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据