期刊
CURRENT OPINION IN PHARMACOLOGY
卷 7, 期 4, 页码 360-366出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2007.04.004
关键词
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gamma-Glutamyltransferase, a key enzyme of GSH metabolism, can modulate crucial redox-sensitive functions, such as antioxidant/antitoxic defences and cellular proliferative/apoptotic balance, with potential implications in tumour progression and drug resistance. Recent studies have elucidated the mechanisms of GGT involvement in various pathological processes suggesting its potential role as therapeutic target and diagnostic/prognostic marker.
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