期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 394, 期 1, 页码 235-244出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-009-2666-3
关键词
Ion mobility; Ion mobility-mass spectrometry; Mass spectrometry; Collision cross section; Conformation space; Oligonucleotides; Carbohydrates; Peptides; Lipids
资金
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [0850976] Funding Source: National Science Foundation
The conformation space occupied by different classes of biomolecules measured by ion mobility-mass spectrometry (IM-MS) is described for utility in the characterization of complex biological samples. Although the qualitative separation of different classes of biomolecules on the basis of structure or collision cross section is known, there is relatively little quantitative cross-section information available for species apart from peptides. In this report, collision cross sections are measured for a large suite of biologically salient species, including oligonucleotides (n=96), carbohydrates (n=192), and lipids (n=53), which are compared to reported values for peptides (n=610). In general, signals for each class are highly correlated, and at a given mass, these correlations result in predicted collision cross sections that increase in the order oligonucleotides
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据