期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 392, 期 5, 页码 861-864出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-008-2354-8
关键词
Aptamer biosensor; Platelet-derived growth factor; Immunoglobulin E; In situ monitoring; Electrochemical impedance spectroscopy
We have successfully developed the first prototype of an electrochemical protein biosensor using polypyrrole as the substrate and doped aptamer as the probe. The sensitivity for a specific target is 10 ng/ml. Two targets, platelet-derived growth factor and immunoglobulin E, have been tested. In both cases the sensor exhibited high specificity and the signal was found to increase as the target concentration increased.
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