期刊
JOURNAL OF NEURO-OPHTHALMOLOGY
卷 27, 期 3, 页码 176-179出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/WNO.0b013e31814b1ac4
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Background: The residual peripapillary retinal nerve fiber layer thickness (PRNFLT) corresponding to no light perception vision from long-standing non-glaucomatous optic neuropathies has not been documented. Such a benchmark would be useful information because PRNFLT is being used as an indicator of the visual recovery potential in patients with optic neuropathies. Methods: By means of optical coherence tomography (OCT) using a fast RNFL thickness protocol, we determined the PRNFLT in 8 patients with no light perception (NLP) for at least 1 year from acquired nonglaucomatous optic neuropathies. All patients underwent an assessment of visual acuity, color vision, visual field, pupillary reactions to light stimulation, and ophthalmoscopy. Results: Four of the 8 patients had a normal fellow eye. The average PRNFLT in the 4 normal eyes was 97.90 mu m (range 94.82-100.89 mu m), whereas the average PRNFLT in 8 of the 9 eyes with NLP was 45.42 mu m (range 37.65-51.46 mu m). Conclusions: Eyes with long-standing NLP vision from nonglaucomatous optic neuropathies retain a residual PRNFLT of about 45 mu m as measured by OCT. This should be taken into consideration when using PRNFLT to assess visual prognosis in patients with poor vision from various optic neuropathies.
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