Experience With Daptomycin in Staphylococcus Bone and Joint Infections Case Series and Emergence of Nonsusceptibility

Daptomycin, an antibiotic approved for the treatment of soft tissue infections, bacteremia, and right-sided endocarditis, is sometimes used for nonapproved indications when treatment options are limited. We summarize the use of daptomycin in the treatment of 11 cases of bone and/or joint infections. Treatment outcome was successful in 3, unsuccessful in 4, and not evaluable in 4.