期刊
ANALYST
卷 139, 期 18, 页码 4525-4531出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4an00604f
关键词
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资金
- National Basic Research Program of China [2012CB933402]
- National Natural Science Foundation of China [51161120361, 21274074]
Electrochemical detection of dopamine plays an important role in medical diagnosis. In this paper, we report a three-dimensional (3D) interpenetrating graphene electrode fabricated by electrochemical reduction of graphene oxide for selective detection of dopamine. This electrochemically reduced graphene oxide (ErGO) electrode was used directly without further functionalization or blending with other functional materials. This electrode can efficiently lower the oxidation potential of ascorbic acid; thus, it is able to selectively detect dopamine in the presence of ascorbic acid and uric acid. The ErGO-based biosensor exhibited a linear response towards dopamine in the concentration range of 0.1-10 mu M with a low detection limit of 0.1 mu M. Furthermore, this electrode has good reproducibility and environmental stability, and can be used to analyse real samples.
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