期刊
ANALYST
卷 139, 期 11, 页码 2714-2720出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4an00548a
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资金
- National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health (NIH) [R21EB015722]
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R21EB015722] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM106016] Funding Source: NIH RePORTER
Touch spray, a spray-based ambient in situ ionization method, uses a small probe, e.g. a teasing needle to pick up sample and the application of voltage and solvent to cause field-induced droplet emission. Compounds extracted from the microsample are incorporated into the sprayed micro droplets. Performance tests include disease state of tissue, microorganism identification, and therapeutic drug quantitation. Chemical derivatization is performed simultaneously with ionization.
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