期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 71, 期 9, 页码 2242-2247出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.70228
关键词
antibacterial nanoparticles; scallop; drug delivery system
To develop a new drug delivery system, antibacterial 50-900 nm nanoparticles of shell and internal organs from scallops collected off Huksan-Island, Korea, were prepared by dry grind technology respectively. The diameters, identities, and conformations of the scallop shell and internal organ particles were determined with a particle-size analyzer and by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and Raman spectroscopy. The antibacterial properties of the nanoparticles from scallop shell were investigated in the absence and the presence of scallop-shell extract. Bacterial growth was reduced with the supernatant of the nanoparticle scallop-shell extract. Also, the nanoparticles from scallop shell were much more effective as a skin softener than was powder. These facts provide us with guidelines for the study of the size-dependent properties of functional materials as well as for further applications to drug delivery systems (DDSs) and cosmetic raw materials.
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