期刊
ANALYST
卷 139, 期 7, 页码 1618-1621出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3an01482g
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资金
- National Science Foundation of China: Investigation of Fast Pathogen Detection Based on Novel Macroporous Chips Technology [21275105]
- National Recruitment Program of Global Experts (NRPGE)
- Hundred Talents Program of Sichuan Province (HTPSP)
- Sichuan University
In this communication, we present a nano-graphite-DNA hybrid sensor for fluorescent detection of mercury(II) ions in aqueous solution for the first time. Furthermore, an amplification strategy based on nano-graphite for Hg2+ detection by using DNase I was demonstrated. The proposed amplified assay was simple and cost-effective with a limit of detection (LOD) for Hg2+ of 0.5 nM, which was about 20-fold lower than that of traditional unamplified homogeneous assays. We further demonstrated its practical application to detect Hg2+ in a real sample.
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