期刊
ANALYST
卷 138, 期 16, 页码 4574-4578出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3an00447c
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资金
- EPSRC [EP/H028757/1]
- Engineering and Physical Sciences Research Council [EP/H028757/1] Funding Source: researchfish
Using the bianalyte method we unambiguously demonstrate that a single gold nanosphere on a metal film junction, in the so-called nanoparticle on a mirror configuration, is capable of single molecule detection with surface-enhanced Raman spectroscopy (SERS). Also this configuration serves as a convenient and highly sensitive SERS sensor for detection of biomolecules. Such simple nano-junction based systems are ideal for chemical and biomedical analysis.
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