期刊
ANALYST
卷 137, 期 5, 页码 1055-1067出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2an15736e
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资金
- Secretaria d'Universitats i Recerca of the DEC of the Generalitat de Catalunya [CTP 00032]
- INTERREG SUDOE IVB
- FEDER [SOE1/P1/E129 ALARMTOX, RTA2008-00084-00-00]
- INIA
- MICINN
- European Social Fund through the Ramon y Cajal programme
- European Social Fund through the Juan de la Cierva programme
- Comissionat per a Universitats i Recerca of the DIUiE of the Generalitat de Catalunya
This article gives an overview of the biosensors for the analysis of mycotoxins, marine toxins and cyanobacterial toxins, describing in depth the electrochemical biosensors that incorporate nanobiotechnological concepts. Firstly, it presents tailor-designed biomolecules, such as recombinant enzymes, recombinant antibody fragments and aptamers as novel biorecognition elements in biosensors. It also reviews the use of metallic nanoparticles (NPs) and carbon nanotubes (CNTs) aiming at improving the electrochemical transduction strategies. Finally, the exploitation of magnetic particles (MPs) as immobilisation carriers in flow-systems and the development of arrays are also described. The incorporation of these nanobiotechnological concepts provides with electrochemical biosensors with superior analytical performance in terms of specificity, sensitivity, stability and analysis time.
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