A fishnet electrochemical Hg2+ sensing strategy based on gold nanoparticle-bioconjugate and thymine-Hg2+ -thymine coordination chemistry

A novel electrochemical biosensing strategy based on a three-dimensional fishnet of DNA-linked nanoparticle supramolecular structure triggered by the analyst for detection of Hg2+ has been designed. The detection limit is 7.38 pM and the sensor's selectivity and facility have been significantly improved.