期刊
DIABETES RESEARCH AND CLINICAL PRACTICE
卷 77, 期 3, 页码 471-478出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2007.02.002
关键词
metabolic syndrome; Australia; insulin resistance; cardiovascular disease risk; central obesity; AusDiab
Objective: To compare the prevalence of the Metabolic Syndrome (MetS) defined by four definitions and to determine which definition best identifies those at high cardiovascular disease (CVD) risk and with insulin resistance. Methods: AusDiab is a population-based survey of 11,247 Australians. Participants had anthropometry, blood pressure, and fasting biochemistry. Ten-year CVD risk was calculated. Results: The prevalence of the MetS using the ATPIII, WHO, IDF, and EGIR definitions was 22.1% (95%Cl: 18.8, 25.4), 21.7% (19.0, 24.3), 30.7% (27.1, 34.3), and 13.4% (11.8, 14.9), respectively. Comparing those with to those without the MetS, the odds ratios (95%Cl) for having a 10year CVD risk >= 15% were 6.6 (5.4,8.2),5.5 (4.7,6.5),5.6 (4.8,6.6), and 3.5 (3.0,4.1), for the WHO, ATPIII, IDF, and EGIR definitions, respectively. The population attributable risk (PAR) of high CVD risk due to the MetS was highest for the IDF (23.4%). Insulin resistance was detected in 56.1, 69.7, 50.9, and 91.1 % of those meeting the ATPIII, WHO, IDF, and EGIR definitions, respectively. Conclusion: The WHO definition was associated with the greatest CVD risk, but is not practical for clinical use. The higher PAR due to the IDF definition, with only slightly lower CVD risk than WHO, and clinical utility of the IDF definition, indicates that it may be a useful tool for CVD prevention. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据