期刊
ANALYTICA CHIMICA ACTA
卷 599, 期 1, 页码 7-15出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2007.08.003
关键词
clinical analysis; potentiometry; biosensors; biocatalysis; bioaffinity
A large variety of potentiometric biosensors is developed using biocatalytic and bioaffinity-based biosensing schemes. However, only few of them could be applied for the biomedical analysis. The most promising are those for the detection of main products of protein metabolism, namely urea and creatinine. A novel group of potentiometric biosensors is constituted by bioaffinity-based devices that could be used for immunoassays or genoanalysis. This paper reviews the recent trends in these fields as well as discusses advantages, limitations and pitfalls of the developed biosensors. Some potentiometric biosensors useful for real biomedical analysis are reported in detail. (c) 2007 Elsevier B.V. All rights reserved.
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