期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 72, 期 19, 页码 7343-7351出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo071210y
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资金
- FIC NIH HHS [U19 TW007401, 1U01 TW 007401-01, U01 TW007401] Funding Source: Medline
[GRAPHICS] Callophycoic acids A-H (1-8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene-benzoic acids and diterpene-phenols in macroalgae. Compounds 1-10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides previously isolated from this red alga.
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