期刊
TETRAHEDRON-ASYMMETRY
卷 18, 期 19, 页码 2300-2304出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2007.09.020
关键词
-
The combination of (Sa)-binam-L-Pro (5 mol %) and benzoic acid (10 mol %) was used as catalysts in the direct aldol reaction between diff. erent aliphatic ketones and 4-nitrobenzaldehyde under solvent-free reaction conditions. Three diff. erent procedures are assayed: magnetic stirring (method A), magnetic stirring after previous dissolution in THF and evaporation (method B), and ball mill technique (method C), methods A and B being the simplest. These reaction conditions allowed us to reduce the amount of required ketone to 2 equiv to give the aldol product in similar reaction times and regio-, diastero-, and enantioselectivities than in organic or aqueous solvents. (c) 2007 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据