期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 72, 期 20, 页码 7783-7786出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo070983j
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[GRAPHICS] The copper-catalyzed cycloisomerizations of 2-pyridyl-substituted propargylic acetates and its derivatives are described, which offer an efficient route to C-1 oxygenated indolizines with a wide range of substituents under mild reaction conditions. The presented method could be readily applied to the synthesis of indolizinones through a cyclization/1,2-migration of tertiary propargylic alcohols.
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