期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 51, 期 10, 页码 3752-3755出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00572-07
关键词
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Brucella suis histidinol dehydrogenase (HDH) can be efficiently targeted by substrate analogues. The growth of this pathogen in minimal medium was inhibited and the multiplication in human macrophages was totally abolished in the presence of the drugs. These effects have been shown to be correlated with the previously described inhibition of Brucella HDH activity.
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