期刊
NATURE GENETICS
卷 39, 期 10, 页码 1200-1201出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ng2131
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资金
- NCRR NIH HHS [U54 RR020278] Funding Source: Medline
- NEI NIH HHS [EY11309, N01-EY-0-2127, R01 EY011309] Funding Source: Medline
The association of variants in complement factors H and B with age-related macular degeneration has led to more intense genetic and functional analysis of the complement pathway. We identify a nonsynonymous coding change in complement factor 3 that is strongly associated with risk of age-related macular degeneration in a large case-control sample.
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