Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients

The purpose of the present study was to quantify the mechanical effect of genioglossus stimulation on flow mechanics and pharyngeal cross-sectional area in patients with obstructive sleep apnoea, and to identify variables that determine the magnitude of the respiratory effect of tongue protrusion. The pressure/flow and pressure/cross-sectional area relationships of the velo- and oropharynx were assessed in spontaneously breathing genioglossus stimulation. Genioglossus contraction decreased the critical pressure significantly from 1.2 +/- 3.3 to ranging -0.6-5.9 cmH(2)O. -0.7 +/- 3.8 cmH(2)O with individual decreases was not affected by genioglossus contraction.The pharyngeal response to genloglossus stimulation was related to the magnitude of advancement of the posterior side of the tongue, but not to the severity of sleep apnoea, critical pressure, compliance or the shape and other characteristics of the velopharynx. Genioglossus contraction enlarges both the velo- and the oropharynx and lowers the critical pressure without affecting pharyngeal stiffness.The response to genioglossus stimulation protrusion achieved rather than on inherent depends upon the magnitude of tongue characteristics of the patient and their airway.