Three new cadinene derivatives from Xenia puerto-galerae

Chromatographic investigation of an acetone extract of the octocoral Xenia puerto-galerae afforded three new cadinene sesquiterpenes; 8-epi-xenitorin A (1), 10-epi-xenitorin C (2), and 7-isopropenyl-4, 10-dimethyl-2,3,4,5-tetrahydronaphthalene (3), in addition to four known cadinene analogs (4, 11-13) and six xenicanes (5-10). The structures were elucidated through spectroscopic analysis, especially 2D NMR. A biogenetic pathway of 1-3 and analogs was proposed.