4.4 Review

Liver transplantation using hepatitis B core antibody-positive grafts: Review and university of Tokyo experience

期刊

DIGESTIVE DISEASES AND SCIENCES
卷 52, 期 10, 页码 2472-2477

出版社

SPRINGER
DOI: 10.1007/s10620-006-9656-5

关键词

hepatitis B virus; De novo hepatitis; living donor liver transplantation; hepatitis B core antibody; hepatitis B immunoglobulin

向作者/读者索取更多资源

Hepatitis B surface antigen-negative and hepatitis B core antibody-positive grafts were considered unsuitable for transplantation. The number of potential recipients for liver transplantation now exceeds that of potential donor organs, which has led us to reevaluate the feasibility of these grafts. Several strategies involving prophylactic administration of hepatitis B immunoglobulin and/or lamivudine to transplant recipients have been proposed. At the University of Tokyo, we have continued to use hepatitis B immunoglobulin monoprophylaxis with zero recurrence. In this article we report our experience with the use of hepatitis B surface antigen-negative/hepatitis B core antibody-positive grafts with hepatitis B immunoglobulin monotherapy. We conducted a review of the literature regarding the feasibility of these grafts to reconfirm optimal prophylactic strategies for preventing de novo hepatitis B virus infection in transplant recipients.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据