期刊
BRITISH JOURNAL OF NUTRITION
卷 98, 期 -, 页码 S41-S45出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114507832995
关键词
fatty acid; fish oil; omega-3; eicosanoid; lipid raft; T cell; lymphocyte; antigen presentation; lipid body; inflammation
Fatty acids are known to play diverse roles in immune cells. They are important as a source of energy, as structural components of cell membranes, as signaling molecules and as precursors for the synthesis of eicosanoids and similar mediators. Recent research has suggested that the localization and organisation of fatty acids into distinct cellular pools has a direct influence on the behaviour of a number of proteins involved in immune cell activation, including those associated with T cell responses, antigen presentation and fatty acid-derived inflammatory mediator production. This article reviews these studies and places them in the context of existing literature in the field. These studies indicate the existence of several novel mechanisms by which altered fatty acid availability can modulate immune responses and impact upon clinical outcomes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据