Flavonoids, coumarins and Triterpenes from the aerial parts of Cnidoscolus texanus

Phytochemical investigation on Cnidoscolus texanus led to the isolation of 26 compounds, which included 15 flavonoids (115), three coumarins (16-18), three coumaric acid derivatives (19-21), four triterpenoids (22-25), and one phytosterol (26). Among them, aromadendrin 7-O-(4 ''-O-p-E-coumaroyl-beta-glucopyranoside) (1), aromadendrin 7-O-(3 '',6 ''-di-O-p-E-coumaroyl-beta-glucopyranoside) (2), and naringenin 7-O-(4 ''-O-p-Z-coumar- oyl-beta-glucopyranoside) (3) are new compounds. Their structures were determined by spectroscopic and chemical methods. All flavonoids were found to be inactive against DNA topoisomeraseoyl-beta-glucopyranoside) (3) are new compounds. Their structures were determined by spectroscopic and chemical methods. All flavonoids