We study macroscopic quantum tunneling (MQT) in c-axis twist Josephson junctions made of high-T-c superconductors in order to clarify the influence of the anisotropic order parameter symmetry (OPS) on MQT. The dependence of the MQT rate on the twist angle gamma about the c axis is calculated by using the functional integral and the bounce method. Due to the d-wave OPS, the gamma dependence of standard deviation of the switching current distribution and the crossover temperature from thermal activation to MQT are found to be given by cos 2 gamma and root cos 2 gamma, respectively. We also show that a dissipative effect resulting from the nodal quasiparticle excitation on MQT is negligibly small, which is consistent with recent MQT experiments using Bi2Sr2CaCu2O8+delta intrinsic junctions. These results indicate that MQT in c-axis twist junctions becomes a useful experimental tool for testing the OPS of high-T-c materials at low temperature, and suggest high potential of such junctions for qubit applications.
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