期刊
BLOOD COAGULATION & FIBRINOLYSIS
卷 18, 期 7, 页码 595-598出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MBC.0b013e3281067fb2
关键词
anticoagulation; multiple myeloma; survival; thalidomide; venous thromboembolism
类别
Venous thromboembolism (VTE) is a cancer complication associated with poor survival. We have analyzed the prognostic impact of the development of a thrombotic episode in newly diagnosed multiple myeloma patients who received chemotherapy either with or without thalidomide on our Total Therapy 2 protocol. Of 668 patients enrolled, 155 developed VTE complication during treatment. The overall and event-free survival of patients who experienced VTE was not inferior. Of interest, we observed that patients who received intensive chemotherapy without thalidomide but developed a thrombosis experienced a significantly longer event-free survival compared with those without VTE (P= 0.02). Our observation suggests a possible beneficial effect of anticoagulation on survival in patients treated for myeloma. Blood Coagul Fibrinolysis 18:595-598 (c) 2007 Lippincott Williams & Wilkins.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据