期刊
ADVANCED MATERIALS
卷 19, 期 19, 页码 2847-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200602487
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资金
- NIDCR NIH HHS [R01 DE013023-06A2, R01 DE013023] Funding Source: Medline
Microfluidic devices were fabricated from silk ribroin using an aqueous molding process adapted from soft lithography. The process results in mechanically robust, patent devices with macroscopic fluidic connections. Hepatocytes were seeded in the device and perfused for up to five days during which they exhibited liver-specific functions equivalent to that observed for standard tissue culture substrates.
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