期刊
APPLIED BIOCHEMISTRY AND MICROBIOLOGY
卷 43, 期 6, 页码 611-615出版社
PLEIADES PUBLISHING INC
DOI: 10.1134/S0003683807060075
关键词
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To impart antimicrobial activity to surgical sutures, weaved polyester fibers are coated with poly-3-hydroxybutyrate (PHB), containing the antimicrobial agent furazolidone (FZ). The prolonged FZ effect (7-14 days) is achieved by two-step application of a sheath, constituting 10% of the suture weight and containing 2-6% FZ. The sheath structure and antimicrobial activity of sutures can be modified by the introduction of other biocompatible and biodegradable polymers.
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