期刊
DEVELOPMENTAL CELL
卷 13, 期 5, 页码 609-622出版社
CELL PRESS
DOI: 10.1016/j.devcel.2007.10.007
关键词
-
资金
- NIGMS NIH HHS [R01 GM050526, R01 GM068966-05, R01 GM070902, R01 GM068966, GM50526, GM68966] Funding Source: Medline
The par genes were discovered in genetic screens for regulators of cytoplasmic partitioning in the early embryo of C. elegans, and encode six different proteins required for asymmetric cell division by the worm zygote. Some of the PAR proteins are localized asymmetrically and form physical complexes with one another. Strikingly, the PAR proteins have been found to regulate cell polarization in many different contexts in diverse animals, suggesting they form part of an ancient and fundamental mechanism for cell polarization. Although the picture of how the PAR proteins function remains incomplete, cell biology and biochemistry are beginning to explain how PAR proteins polarize cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据