期刊
NATURE REVIEWS NEUROSCIENCE
卷 8, 期 11, 页码 859-871出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn2254
关键词
-
资金
- Medical Research Council [G9900989] Funding Source: Medline
- MRC [G9900989] Funding Source: UKRI
- Medical Research Council [G9900989] Funding Source: researchfish
The cranial motor nerves control muscles involved in eye, head and neck movements, feeding, speech and facial expression. The generic and specific properties of cranial motor neurons depend on a matrix of rostrocaudal and dorsoventral patterning information. Repertoires of transcription factors, including Hox genes, confer generic and specific properties on motor neurons, and endow subpopulations at various axial levels with the ability to navigate to their targets. Cranial motor axon projections are guided by diffusible cues and aided by guideposts, such as nerve exit points, glial cells and muscle primordia. The recent identification of genes that are mutated in human cranial dysinnervation disorders is now shedding light on the functional consequences of perturbations of cranial motor neuron development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据