期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 17, 期 21, 页码 5868-5871出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.08.012
关键词
abietane-type diterpene; taxodistine A; taxodistine B; tubulin
Two new abietane-type diterpenes, taxodistines A (1) and 13 (2), have been isolated by the guidance of inhibitory effect of tubulin polymerization from the fruits of Taxodium distichum and the structures were elucidated by using 2D NMR data. Taxodistine B (2) showed inhibition of tubulin polymerization. (c) 2007 Elsevier Ltd. All rights reserved.
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