4.5 Article

Taxodistines A and B, abietane-type diterpenes from Taxodium distichum

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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 17, 期 21, 页码 5868-5871

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.08.012

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abietane-type diterpene; taxodistine A; taxodistine B; tubulin

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Two new abietane-type diterpenes, taxodistines A (1) and 13 (2), have been isolated by the guidance of inhibitory effect of tubulin polymerization from the fruits of Taxodium distichum and the structures were elucidated by using 2D NMR data. Taxodistine B (2) showed inhibition of tubulin polymerization. (c) 2007 Elsevier Ltd. All rights reserved.

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