期刊
SURGICAL ONCOLOGY-OXFORD
卷 16, 期 3, 页码 149-156出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.suronc.2007.09.005
关键词
neuroblastoma; MYCN; tumor regression
资金
- NIDDK NIH HHS [F31 DK079422, R01 DK61470] Funding Source: Medline
Neurobtastomas continue to remain a ctinical challenge, despite advances in multimodal. therapy. Currently, studies are aimed at novel, targets for neuroblastoma directed toward poor prognostic indicators such as the MYCN oncogene and marked angiogenesis. There have also been recent discoveries in neuroblastoma pathogenesis involving epigenetic regulation and retinoic acid therapy. Understanding the intricate complexities of this tumor may lead to innovative agents for more effective combinational therapy. Published by Elsevier Ltd.
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