期刊
BIOMATERIALS
卷 28, 期 32, 页码 4845-4869出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biomaterials.2007.07.013
关键词
PEEK; polyetheretherketone; composites; hip resurfacing; spine; fracture fixation
资金
- NIAMS NIH HHS [R01 AR047904, R01 AR47904, R01 AR047192-06, R01 AR047904-06, R01 AR047192] Funding Source: Medline
Since the 1980s, polyaryletherketones (PAEKs) have been increasingly employed as biomaterials for trauma, orthopedic, and spinal implants. We have synthesized the extensive polymer science literature as it relates to structure, mechanical properties, and chemical resistance of PAEK biomaterials. With this foundation, one can more readily appreciate why this family of polymers will be inherently strong, inert, and biocompatible. Due to its relative inertness, PEEK biotnaterials are an attractive platform upon which to develop novel bioactive materials, and some steps have already been taken in that direction, with the blending of HA and TCP into sintered PEEK. However, to date, blended HA-PEEK composites have involved a trade-off in mechanical properties in exchange for their increased bioactivity. PEEK has had the greatest clinical impact in the field of spine implant design, and PEEK is now broadly accepted as a radiolucent alternative to metallic biomaterials in the spine community. For mature fields, such as total joint replacements and fracture fixation implants, radiolucency is an attractive but not necessarily critical material feature. (c) 2007 Elsevier Ltd. All rights reserved.
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