期刊
PHOTOCHEMISTRY AND PHOTOBIOLOGY
卷 83, 期 6, 页码 1283-1300出版社
WILEY
DOI: 10.1111/j.1751-1097.2007.00196.x
关键词
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This review deals with the biophysical aspects of flavin-based photosensors, comprising cryptochromes, LOV (Light, Oxygen and Voltage) and BLUF (Blue Light sensing Using FAD) proteins. Special emphasis is given to structural issues, photo-cycle quantum yields and energetics, mechanism of the light-triggered reactions, early stages in signal transduction and oligomeric states of the light sensing protein modules. For BLUF and LOV domains important parallels are emerging, despite their different alpha/beta fold arrangement, whereas there is increasing evidence for a mechanicistic and functional splitting of the cryptochrome family.
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